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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b9ece0927b92af76c92835be48bc14cff45611fc7af140b8372fcb5f4a1e99e' 
  AND token = 'thN7V3uH4vyOPna6VLMouORxBTWRRTZUrfzNW4Ms3hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}