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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7720ce183852419b34f44069b741838ea772fdb23aeb36b9ca8b386447e68bb8' 
  AND token = 'AxlMKM2BxcjYKKbN8S093PetwD69o6VnRb7MS3pDFcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}