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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb7c380772e7fc274e0f7a9c0046ca9e448746e4a84fb8d088e40cbcbda320c5' 
  AND token = '5gSqDS6Vt7ZVeMSvGHhLI1tkjYY9Ev2B/9ghnElpdoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}