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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7a2a78458ba8fdab60ec5dd77dc0d5e0b63ef70d1956b4949c8452570f8f718' 
  AND token = 'gmgZegO+YHnLXBa2dcnTLgDAYRUFtUVQeZMy/pNQwf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}