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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a647024c4e5815a3ac68f0f0d0e6513eac754cd20fbdfd55d0069e0207559324' 
  AND token = 'WI2GCBMyoZSIu2etWiQk/wLCxSMeLo39t0gzu9PFuKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}