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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0307d314a78c8dbc5cc59235bcd5451b3ac8ca86de0df547b4b59147008062e2' 
  AND token = 's8+YqDxjN3QqLQF/o/ZWXN2XqIHc/Q9r9paZqBRmYAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}