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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d2ccc2d642cfd6fc59de7b05d43ae949003d15ef87760c220c17b322205f62' 
  AND token = 'w08TDk3JzyFDL0LSk5he4poaJdEnbKGqCdFXkKfIKMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}