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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a3e0956702e8cfe5b87632ff9b6f2539c8882993893749a1f9ab46ec0b6a5d' 
  AND token = 'RV6VTJpfgg6qWH6H12XLYLL6V+AtW7lW6pwex9Dup0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}