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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e13d3c9fbc4851e5c1edb6a48e534016e6ff11e35c709a8a07a3fd74125d902' 
  AND token = 'hMPkSsvrGiaQvlOgFkmZ8w1wV4p7VTob1kjUHTx0I5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}