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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1140c80f2fc52a3d8ef6997ac5bc472139876ccba146e116b1b3de57038d92a3' 
  AND token = 'hP63YYegZU5FF3XJpyHUiPh5Tv8uo5AWBUMDhtMcfg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}