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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b06837e02eac8f092095004039f5b79bfc13d5fb315e793dcb7e76f8dec7dc' 
  AND token = 'x4QkfG144M9PgxyYr7tfgvabkyNf/Ck9WSfSa3xPcUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}