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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e015cbd6b8fef27b14ffc6fb6d05f5d4704143123d0dce516740f881beefe5' 
  AND token = 'Q7aAz+iAd5euUq75MYZ/pLFz19MpJd5CRM2Oz/YfTCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}