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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49824712ae4c5ada1f59845886d2cdd8c54d3619bac98e702551dc524c51fcb0' 
  AND token = '2XR7+uD+xfM1ugHH6xDj7yb04EyrE6baAFnmd74AS4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}