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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a4b61de056ed7853aeb14a049b30622d4584a82f797de3d945b243fb2c1bc1' 
  AND token = 'ESwiyI5QdxaDjqesfDqs34sTk2GJGdho4jidmJpV8gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}