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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be068b03a774038ece2670e830f47897c7993146c5b3e088899915be0a25c173' 
  AND token = 'PzoBKwzUcYvVUP9Yt6Gn0T3QI9oagolGDwjQca0gxX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}