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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2681db3ae751708602f6f977e8958c8e3e0934c916f24b3283d53d104d1259d8' 
  AND token = 'oUW4gLYbQFRx8qVcCftjZg7YZ0UXdACkm1om3MMYoEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}