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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4b3ab5b17b8a75395985fe4fe34a48303f83ca4aa6018c33c7f73c1787d762' 
  AND token = 'Mp8MEydmDgKY42fIlfC8tF8CVkeoFq5qTU/5bsmIk2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}