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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d69d187f76d55f771c85c6a93162806f83569a72cc12c0867f38da8e6cd9bb' 
  AND token = 'NUAh5rl8zgbeawbKW1R4WM3GfdF3n45VtTuPGBLx+Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}