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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d1dd8b401dad4d8cb7baaf0b85073279ca90835c1b5a76b637c399cbffc7e38' 
  AND token = 'ju+VAZU2a2BgcTXvKIsLR58LGApJQ3AIYo50LVc9e9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}