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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380582ca178e2b68bde0e5e084c3fac3ad416add766b6da98d9e4d3a07fb8114' 
  AND token = 'MffqFTJVC0eyfWzCiWJIeluxkpechyc3AuQm/REAVAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}