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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e7e833623ef54bb96ee99e2cf8bdde9aabb441ea979c3417088c3ac60023de' 
  AND token = 'K+RYYz6HNJE7zqAed6DVjGX00IqUBEpjW/FsbekSAw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}