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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f759ef4b9fae7c49b35ee664992d82509b9c78bc1fbbaa474b46eafc799e125' 
  AND token = 'EH+Hre4faMY4QP7QJ+SJ56SWiZ8xuMmaxRM7R2q0nsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}