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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a34dd5d19a9e3bfad0f8c3e62fd501e21d58fa280c6b8b4ddb06858b01300b' 
  AND token = 'SsIH4xaor+v4107F2RpvC4uDfVSs4LdrJe8lCNu6knU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}