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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2785bb831189070a2b0a0078b0467893ba9bada727195ed558a1e994ce21637' 
  AND token = 'ql62Ic95Y/Fsz+Vf5tfl13TmfdYvT8HK81GMdwVO9p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}