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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308ea0a4cb04271e8a1dc76babc3a4fa27e6a7b167b49770175ce9f3211e5a3d' 
  AND token = 'rXyHLHiLTgQlDyrBAN5xdQx0ZTO9v2S14k67SzXNfh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}