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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e879dc16b918b0d4e0ff9fe927d4bfd268e5c3761b4a4738701c10e3497e1484' 
  AND token = 'PKTStIP1+axXpiyKbyjmwMlA72Q4/cVsJ4fO2AwB3wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}