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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6356f5a311c642bcf53cbd6014fc608266943fed6d292db4e8f460034e45eec6' 
  AND token = 'ye/3Tm5GXzz4u+esKwvn2yi6isK2O0I6WBPbf/k/ZYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}