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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8f00fc6e84562038cbfe620ba5d10ada38766d573369011000c60b58d6f6ae' 
  AND token = 'G6ZEXQl0+sIhh7Z3VPzHmGQd/nluTzQTEpAZn5oxzl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}