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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45a2f02199fb0e98c30d5e3195aed6fb04ab916f0dfe86aafdf465ceb4e5bb0' 
  AND token = 'UmTDs9KM1292neArLK5/nJeF8xlFOziSvLgTXqwUo5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}