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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cc4a5e9eed81ce8903afddfb3e721830d255bd14fde9889d5600a2ae9ef8c0c' 
  AND token = '4SbY/WeTPVPB7H60+sm/All44MymLnPOhLi6ENTEexY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}