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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61db003177d64597e0741d9e2560a60fb71517c005d6f8dfb01e47eb9d3e2340' 
  AND token = 'v4Bf8v+dfG6C2vDdbBT0+UILzkvR4l4IbRrF8XCzfNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}