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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45cfec6ec652bfc9f57036b732e734a5448467da189607806f94316187535f2' 
  AND token = 'KVC5uISIJVrzPVGN0p6RRCscmtnva8sXgCdS+E5oT+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}