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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a667b1ba46eddc372d67b485239efa967e9c5a13fdb5a4f961b5a0c6fb031b0' 
  AND token = '0ddUMfm2vT/xvtiJjhx+hcBYo787+G5DjIehBZBd7Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}