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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1bed250a980f9a2daa49b3b8a8084b24b1c50d5f9d62ec5e6407d9259b8383' 
  AND token = 'udkSbCmS0UlAJwUNnUbigPrj7nTCp6ObfwkOSKJq9Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}