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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd38109547ec1938662d1b6ddd2021d1c216b7c85234d8db341491d39f1a9db5' 
  AND token = 'mlYQhlmMazBAggS4+QLeWYy90VzzK8WuWbOYbkowczc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}