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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede1ffd78d6125304eff102c4cc74ea9a66e4ae870cdfaad7d918504c6a7ee42' 
  AND token = 'DYEiYXCmKzjete41dxGPyPc5eRhXmJDjKPX9dPtcWJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}