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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '739057d526ad10a87ab08231b0837f0f6ae064dec3c2788d7484590011f7f696' 
  AND token = '11H/jO12Hihsll5lmmNjOSspZ9t9//2FkCCLjzhIihM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}