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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2b48e1435f1992806ce0fcc7a42a4afb2211e401b14b976628951b9314c19b' 
  AND token = 'qj5SMpRxyCFkMZjlpRSv9RNF01G29it7p62PSd0xifE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}