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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7d5fb27358a93013ac80c54ede0837a3ecd58c6ca7697891d89a6b08198589' 
  AND token = 'l010WM1r3g8bLAbV21uLHqf60cRRvL1RaSwA1oHDIEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}