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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe18b6b5eb962e3bf82a77b25f86fdd88cafa8087e2dc5edab33edd3005d757' 
  AND token = 'qQSAaFOn2hRrJUmu//lWFh0of3Toa134aB9ttwlx1uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}