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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf9daeb532d106797a525ed9ef23f648f9c8396dc250fbc9dc24709b700d28a' 
  AND token = 'BGHKVA2v4L3S+4v9oUdWbT//HCAsnR843M2t/aOXpds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}