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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f41091d2de774f4713f26d1e032b5d6337ee64d0274d5dbf74a467c7476f701' 
  AND token = 'Ys3lY5DNq99AqcV0OBLQ8N4psUs3hfFl95fzYBACJCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}