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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4a6b67c07bb64e0211c1003725142216cb3a1c0fd09296fc68a6d2614025d5' 
  AND token = 'N+WXteRWNKY9OBmXxZZYMiCOevV4ZmUT6hE/V902biA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}