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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05c9bf93e173474415ce84cb1234501b4f984c30f71bb9d1d5a7a12d5863e0c6' 
  AND token = '1CesnUkebKhTi5eFjrb8eOLVC64YDCDWB+saVDBuh7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}