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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4eb0b9e459675822ede5ef324c2f9985a5c41b5df80769285c71375ca330fd' 
  AND token = 'cIUN4BsTJZK3CzPqlNBsZ9abc5A5+e8CIoSqcFDtyMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}