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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a13b516772cb1367e8deedadd655f5d95921572d06c09e6a52ee91a95c97f5' 
  AND token = 'IjHbOVVnuo6RNAAV52UaI3Ye+oyYL8vxq1WzBQfPG70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}