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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ea3a6777140a725f4c902219abc0043460ff8d614fa16633126f268427f5820' 
  AND token = 'lm66oAB/3kHQwz50+Cmp5mnpMsN8tKuRAzaO2y0NTtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}