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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66eded45f29d1df347e7a66af176c1c1f340dd900ed1707b959c1bbee472951' 
  AND token = '/QFMGxX2kuiNtmfYa+tUchITp/5PwseEelt3fCP12aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}