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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60e63329b3a7108347fbd9ad3e6606c68b4cb4aa16dae890342bf979ed4c3dab' 
  AND token = 'ZQyPPs2Mkr81zK6f1+7/oyHOmxzl+QmG4Ai8r+sxU0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}