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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41ffbf3925e598b5595526657dd521fb089ce8edb30521efd54923b288b8282' 
  AND token = 'yPZk94clPK3WObtlXho+oz6tJUOX9MBddW1F7UsIDGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}